Mit Beiträgen zahlreicher Fachwissenschaftler
This book addresses chemical and biological aspects related to sesquiterpene lactones (STLs). Experts in different fields have been invited to contribute on this class of compound's chemistry, isolation and identification, biological activities (antibacterial, antifungal, antiviral, antitrypanosomal, antileishmanial,antiplasmodial, antiproliferative and antiinflammatory), synthesis, biosynthesis, derivatization and QSAR analysis. Taxonomic and chemotaxonomic aspects related to the Asteraceae family are also contributed. The book begins by describing the chemical characteristics of STLs, their classification in different skeleton types, synthesis, distribution in nature and their most important biological properties. An overview of the group's main representatives, based on their importance for human health, as well as an update of the most recently isolated STLs, follow. The authors also provide an overview of the most common methods described in the literature for the extraction, purification, identification and structure elucidation of STLs, while also highlighting more recently developed methods. Furthermore, experts in the field provide an in-depth discussion of the most...
The world faces significant challenges as the population and consumption continue to grow while nonrenewable fossil fuels and other raw materials are depleted at ever-increasing rates. Moreover, environmental consciousness and a penchant for thinking in terms of material cycles have caught on with consumers: the use of environmentally compatible materials and production methods is desired. This volume, Green Materials and Environmental Chemistry: New Production Technologies, Unique Properties, and Applications takes a technical approach to address these issues using green design and analysis. This book provides an overview of the latest developments in environmental chemistry and sustainable materials written by experts in their respective research areas. This interdisciplinary volume offers research with the aim to minimize environmental impacts across all lifecycle phases in the design and engineering of products, processes, and systems as just one possible approach to addressing the larger issue of sustainability that includes environmental, economic, and social aspects.
The rich and diverse architectural traditions of the Eastern Mediterranean and adjacent regions are the subject of this book, including the social and cultural developments of the Byzantine Empire, the Caucasus, the Balkans, and Russia, as well as parallel developments in Crusader and early Islamic architecture.
Infraspecific differentiation. Classification of infraspecific chemical taxa. Nomenclature of infraspecific chemical taxa.
- Incluye la evaluación y la intervención del bebé dentro del contexto de los trastornos del neurodesarrollo. - Describe ampliamente los factores de riesgo pre-, peri- y posnatales, a la vez que profundiza en la prematuridad. - Presenta no solo las condiciones clínicas, sino también el desarrollo de los sistemas vestibular, somato-sensorial, visual o motor-postural, entre otros, así como de las funciones cognitivas y de la realidad psicoafectiva del niño. - Además, describe la vinculación de los trastornos del neurodesarrollo con estos sistemas. - Otorga una gran relevancia a los factores ambientales, tanto en la evaluación como en la intervención, donde la educación de la familia es clave. - Organiza las intervenciones en un nuevo paradigma interdisciplinar. - Cuenta con la participación de profesionales de referencia en distintas disciplinas.Trastornos del neurodesarrollo. Un abordaje integrativo en la evaluación y el tratamiento afronta la complejidad de ciertas condiciones clínicas que afectan a una gran parte de la población infantil. Aporta una visión completa de los trastornos que afectan al bebé antes del nacimiento y durante sus primeros años, y que...
Si bien los avances en el desarrollo de la neuropsicología en Hispanoamérica son bastante significativos, se presentan algunos vacíos, especialmente en el campo de la neuropsicología infantil pues las pruebas existentes no han sido creadas para la población de habla hispana. Neuropsicología infantil pretende llenar esos vacíos e incluye además temas de actualidad; de la mano de sus editores Juan Carlos Arango-Lasprilla, Diego Rivera y Laiene Olabarrieta-Landa, tendremos una paronámica de los trastornos y alteraciones cognitivas en niños y adolescentes, los problemas de aprendizaje, discapacidad intelectual, y nociones básicas para la evaluación neuropsicológica infantil. Explica y analiza la metodología para el estudio de diez pruebas neuropsicológicas, y se describen detalladamente nueve de estas diez pruebas. Presenta además el proceso de diseño y creación de un test dirigido exclusivamente a la población infanto-juvenil de habla hispana. Neuropsicología infantil está diseñado para contribuir a mejorar los estándares de calidad de la evaluación neuropsicológica; con seguridad será de gran utilidad para los profesionales, estudiantes y estudiosos de la...
Orientierung für die neuropsychologische Diagnostik: Das bietet das vorliegende Handbuch neuropsychologischer Testverfahren. Das Kompendium gibt einen systematischen Überblick über neuropsychologische Verfahren im deutschsprachigen Raum. Für den Diagnostiker bietet es vielfältige Hilfen: für eine problembezogene Auswahl adäquater Verfahren, für eine gezielte Sichtung alternativer Designs, für die Untersuchung und Abschätzung testbeeinflussender Faktoren, für den Aufbau von effizienten Diagnosestrategien oder für die theoriegeleitete und kritische Interpretation von Ergebnissen. Der dritte Band des Handbuchs umfasst folgende Themenbereiche: • Neuropsychologische Testverfahren für Kinder und Jugendliche: Sprache, Schriftsprache, Zahlenverarbeitung und Rechnen, Intelligenztests, Entwicklungstests, domänenübergreifende neuropsychologische Testbatterien • Beschwerdenvalidierung • Medikamentöse Einflüsse auf neuropsychologische Funktionen • Psychometrische und statistische Grundlagen für die diagnostische Praxis Jedem der Bereiche des Handbuchs geht ein einführendes Theoriekapitel voraus, das den Rahmen für den theoriegeleiteten Einsatz der Verfahren...
La Educación Infantil engloba el proceso educativo que se inicia con el nacimiento y finaliza con la entrada en la escolarización obligatoria (0-6 años). Es un período crucial y básico en el que la diversidad constituye una constante en las aulas. Esta puede estar provocada por diversas causas: físicas, psíquicas, intelectuales, familiares, sociales, culturales, etc. Atender a la diversidad es dar respuesta a las necesidades educativas que presentan "todos" estos niños y niñas. Este manual está enmarcado en el contexto pedagógico de la diversidad y la escuela inclusiva. Con el objetivo prioritario de ser una obra de utilidad para todos los estudiantes de magisterio del grado de educación infantil, así como de credencial para los profesionales que día a día desarrollan su trabajo en los centros de educación infantil, la obra se ha dividido en dos partes, una sobre aspectos teóricos y otra sobre necesidades educativas, en las que cada capítulo ofrece de forma diferenciada palabras claves, actividades, preguntas de reflexión y conclusiones. En la parte dedicada a las necesidades educativas el lector podrá identificar claramente, mediante apartados específicos,...
Libro especializado que se ajusta al desarrollo de la cualificación profesional y adquisición de certificados de profesionalidad. Manual imprescindible para la formación y la capacitación, que se basa en los principios de la cualificación y dinamización del conocimiento, como premisas para la mejora de la empleabilidad y eficacia para el desempeño del trabajo.
In 1860, Oliver Wendell Holmes pointedly expressed himself to the Massachusetts Medical Society: “I firmly believe that if the whole Material Medica, as now used, could be sunk to the bottom of the sea, it would be all the better for mankind, and all the worst for the fishes.” Should one think the same about the current approach in drug discovery from plants? Probably yes. Despite the spending of billions of US dollars, and three decades of efforts, high-throughput screenings have only allowed the discovery of a couple of drugs. One could have reasonably expected the discovery of an arsenal of drugs from the millions of plant extracts randomly tested, but “hits” can be inactive in vitro or too toxic, some molecules need to be metabolized first to be active, and false-positive and false-negative results are common. The bitter truth is that the robotic approach in discovering drugs from plants has proven, to date, its inability to excavate the hundreds of molecules that will contribute to the health progress of Man. However, one can reasonably see that the last patches of primary rainforest on earth hold still hundreds of spectacularly active drugs that await discovery.
Studies in Natural Products Chemistry, Volume 62 discusses natural products in the plant and animal kingdom that offer a huge diversity of chemical structures resulting from biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. This series covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. - Focuses on the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents sources of new pharmacophores
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
This book focuses on diversity, culture, and ethnicity as they relate to psychological assessment of Hispanics. It is a how-to guide for clinicians, researchers, and instructors working with Hispanic clients. Each chapter contains an overview of cultural considerations needed for assessing the Hispanic client followed by a specific exploration of the assessment measures available and the research that has been conducted on these measures with Hispanic participants. An exploration of the strengths and limitations of each assessment measure is included. Considering that ethnocultural minority individuals who are of Hispanic/Latino origin make up the largest ethnocultural minority group in the United States, guidelines for working with this population are a must. Given that a large subset of this percentage is composed of immigrants many of whom do not speak English or who have learned English as a second language, special considerations for effective psychological assessment are neccessary.This book fills a gap in the scientific literature by consolidating the research on psychological assessment with Hispanic samples into one comprehensive volume and providing simple...
The history of Byzantium pivots around the eleventh century, during which it reached its apogee in terms of power, prestige, and territorial extension, only then to plunge into steep political decline following serious military defeats and extensive territorial losses. The political, economic, and intellectual history of the period is reasonably well understood, but not so what was happening in that crucial intermediary sphere, the social order, which both shaped and was shaped by contemporary ideas and brute economic developments. This volume aims to deepen understanding of Byzantine society by examining material evidence for settlements and production in different regions and by sifting through the far from plentiful literary and documentary sources in order to track what was happening in town and country. There is evidence of significant change: the pattern of landownership continued to shift in favour of those with power and wealth, but there was sustained and effective resistance from peasant villages. Provincial towns prospered in what was an era of sustained economic growth, and, through newly emboldened local elites, took a more active part in public affairs. In the...
El CUMANIN-2, Cuestionario de Madurez Neuropsicológica Infantil-2, es un sistema integrado de exploración neuropsicológica que permite evaluar, de forma sencilla y eficaz, diversas áreas que son de gran importancia para detectar posibles dificultades del neurodesarrollo en unas edades que, por coincidir con el inicio de la etapa escolar, son esenciales en el proceso madurativo de los niños y las niñas.Permite evaluar tres grandes áreas mediante 11 pruebas principales y 3 adicionales:• Desarrollo sensomotor: Atención; Psicomotricidad, Estructuración espacial, Visopercepción y Ritmo.• Memoria y aprendizaje: Memoria visual y Memoria verbal.• Lenguaje: Lenguaje articulatorio, Lenguaje expresivo, Lenguaje comprensivo y Fluidez verbal.• Pruebas adicionales: Lectura, Escritura y Lateralidad.Integra toda esta información en un completo perfil de resultados que ofrece una panorámica de las fortalezas y las áreas de mejora individuales que presenta la persona evaluada.Los baremos se han construido a partir de una amplia muestra controlada de más de 1.100 casos (entre 3:00 y 6:11 años) y se ofrecen en tramos de 4 meses, para aumentar la precisión de las comparaciones...
Famagusta Maritima: Mariners, Merchants, Pilgrims and Mercenaries presents a collection of scholarly studies spanning the thousand year history of the port of Famagusta in Cyprus. This historic harbour city was at the heart of the Crusading Lusignan dynasty, a possession of both Genoa and Venice during the Renaissance, a port of the Ottoman Empire for three centuries, and in time, a strategic naval and intelligence node for the British Empire. It is a maritime space made famous by the realities of its extraordinary importance and influence, followed by its calamitous demise. Contributors are: Michele Bacci, Lucie Bonato, Tomasz Borowski, Mike Carr, Pierre-Vincent Claverie, Dragos Cosmescu, Nicholas Coureas, Marko Kiessel, Antonio Musarra, William Spates, Asu Tozan, Ahmet Usta, and Michael Walsh.
Includes section "Comptes rendus".
A detailed study of the structure of the church of Hagia Sophia in Thessaloniki; from its erection up to the Turkish conquest.
The 5th series starts with the publication of v. 17- which cover the heterocyclic compounds; v. 1-16 cover the acyclic and isocyclic compounds.