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Cellular and Molecular Biology of Bone

Autor: Masaki Noda

Número de Páginas: 590

Written by well-known experts in their respective fields, this book synthesizes recent work on the biology of bone cells at the molecular level. Cellular and Molecular Biology of Bone covers the differentiation of these cells, the regulation of their growth and metabolism, and their death resorption. The authors' special comprehensive treatment of the cellular and molecular mechanisms of bone metabolism makes this book a unique and valuable tool. Cellular and Molecular Biology of Bone provides interested readers-with concise state-of-the-art reviews in bone biology that will enlarge their scope and increase their appreciation of the field. Research in this area has intensified recently due to the increasing incidence of osteoporosis. The editor hopes an understanding of the basic biology of this disease will prove relevant to its prevention and treatment.

Physiology and Pharmacology of Bone

Autor: Gregory R. Mundy , T.john Martin

Número de Páginas: 774

Why have another book in the bone-calcium field? When the idea was first raised that this important area of biomedical research should be given more attention in the review literature, we felt that comprehensive texts recently published and in press were directed at more general audiences and did not address in detail some of the important areas of current investigation. As this field has grown and matured, information has accumulated at such a rapid rate that it has become impossible to keep abreast of all areas by reading the original articles in the scientific literature. Accordingly, we believed there was a void which could be filled by a collection of essays on specific topics in which significant progress had recently been made. Thus, this book is meant to be an up-to-date account of specific topics by investi gators at the forefront of their areas of research. We have tried to review major areas of basic science in the field which have an impact on our understanding of the diseases of bone and mineral. We hope that you will agree that the authors have done an outstanding job, and will find the volume as stimulating to read as we have. San Antonio, TX, USA GREGORY R. MUNDY...

Bone Morphogenetic Proteins: From Local to Systemic Therapeutics

Autor: Slobodan Vukicevic , Kuber T. Sampath

Número de Páginas: 349

Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal is a prerequisite to trigger the growth and differentiation of responding cells in space and time. Bone morphogenetic proteins (BMPs), also called growth and differentiation factors (GDFs), originally identified from bone have been successfully used to regenerate the bone in humans. Most recent preclinical data suggests that BMPs have a potential to provide protection against inflammation and fibrosis in acute and chronic injury of parenchymal tissues when applied systemically to sustain the function of kidney and liver. The application of BMPs from a local to systemic utility is a rapidly growing field, gaining interest among researchers and biotech entrepreneurs. In this volume, we summarize the advances made on the local and systemic use of BMPs including chapters covering the regulation of BMP-signalling pathways, biological actions of BMPs in bone, cartilage and teeth, as well as clinical applications and potential systemic...

Human Biomaterials Applications

Autor: Donald L. Wise , Debra J. Trantolo , David E. Altobelli , Michael J. Yaszemski , Joseph D. Gresser

Número de Páginas: 453

Nineteen cutting-edge articles by leading practitioners review critical issues concerning biocompatible materials-polymers, metals, and other materials-used in or on the human body. Topics range from biopolymers used in controlled release drug delivery systems and synthetic burn-wound dressings to specific orthopedic devices. Each application-oriented article integrates basic science, engineering and medical experience with discussions of quality control. The contributors offer a wealth of valuable data and experience to materials scientists, research engineers, and academic physicians and surgeons. Their many examples provide rich insights into our experience today with a broad spectrum of modern biomaterials applications.

Fundamentals of Craniofacial Growth

Autor: Andrew D. Dixon , David A.n. Hoyte , Olli Ronning

Número de Páginas: 508

This book brings together in one volume selected important topics in craniofacial growth. Topics include: principles of skeletal growth; osteogenesis and its control; formation of the cranial base and craniofacial joints; prenatal development of the facial skeleton; growth of the mandible, nasomaxillary complex, orbit, cranial base, ear capsule, and cranial vault; bone remodeling; muscles; soft tissues; and blood vessels. Fundamentals of Craniofacial Growth contains detailed illustrations and extensive reference lists. Independently authored chapters provide comprehensive reviews encompassing both contemporary and historical perspectives. In addition to medicine and dentistry, contributors provide expertise from such diverse backgrounds as anatomy, biology, biomathematics, embryology, orthodontics, physical anthropology, and plastic and reconstructive surgery.

The Use of Bone Substitutes in Spine Surgery

Autor: R. Gunzburg , M. Szpalski , N. Passuti , M. Aebi

Número de Páginas: 146

Spinal arthrodesis is a generally accepted procedure for the management of patients with a variety of spinal disor ders. The primary goal for spinal fusion is to eliminate the instability of the spine, often caused by trauma, deformity, tumor, inflammation or infection, and common degenera tive deterioration of the motion segments. In many clini FRA paw', cal situations, the optimal solution in restoring the spine's integrity is through surgical intervention. There are many techniques of spinal fusion applicable to the lumbar spine. Posterior (PLIF) and anterior lumbar interbody fusion (ALIF) have been developed and employed to address PLlI' po . . . . . these concerns alone or in combination with various inter nal fixation devices. The anterior column is often recon structed with metallic intervertebral cages or biological Fig. ! Femoral ring allograft (FRA) and posterior lumbar inter implants (allograft or autograft bone) [16, 31]. body fusion (PLlF) spacers The success of every spine fusion procedure depends on the phenomenon of bone healing. Whether the healing process occurs depends on many factors, including the type This paper aims to provide a review of the two newly of...

Handbook of American Indians North of Mexico: A-M

Autor: Frederick Webb Hodge

Número de Páginas: 1002

Factors and Mechanisms Influencing Bone Growth

Autor: Andrew Derart Dixon , Bernard George Sarnat

Número de Páginas: 696

Bone Formation and Repair

Autor: A. Bakr M. Rabie

Número de Páginas: 240

Hardbound. This book deals with research into the molecular biology and biochemistry of the extracellular matrix of mineralized tissues. Special emphasis is given to aspects of research that ultimately lead to the resolution of diseases afflicting man. This volume presents concepts of bone matrix structure and composition, evaluation of BMP expression and biogenesis, BMP in bone and dentine, angiogenesis and its role in wound healing. A dialogue in presentations and discussions highlights the clinical applications of BMP and composite bone grafts in modern reconstructive, implant and orthopedic surgery.This book is directed at biochemists and molecular biologists in the area of mineralized tissues such as bone and dentine. It also caters for clinicians in Dentistry such as dental implant surgery, oral and maxillofacial surgery, periodontists and orthodontists.

Skating, by J. M. Heathcote and C. G. Tebbutt

Autor: John Moyer Heathcote , C. G. Tebbutt

Número de Páginas: 516

The Bone-biomaterial Interface

Autor: John Edward Davies

Número de Páginas: 524

Based on the proceedings of the Bone-Biomaterial Interface Workshop held in Toronto, Canada, December 1990, addresses the questions which have arisen during this period of evolution from inert to active materials in orthopedic, dental, and maxillofacial implants with specific reference to the bone-biomaterial interface. The seven parts of the volume reflect the seven sessions of the workshop, dealing with materials issues, protein adsorption, cell and tissue reactions, mechanical influences on interfacial biology, retrieval analysis, and the industrial context. Annotation copyrighted by Book News, Inc., Portland, OR

The Engineer

Número de Páginas: 550

The Yale Literary Magazine

Número de Páginas: 478

Bone, Volume VIII

Autor: Brian K. Hall

Número de Páginas: 248

Volume 9 features: an overview of mechanisms controlling differentiation and morphogenesis of bone, especially in craniofacial mesenchyme an examination of the important role played by homeobox genes in patterning the skeleton a look at how membrane bones repair themselves a review and analysis of the mechanisms underlying the developmental integration of skeleton and muscles and their role in important future advances in the field an emphasis on fuctional integration an in-depth discussion of gene control

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